Basic & Translational Research

Sensational headlines like “Most cancer is bad luck” aren’t helpful– so what’s the real story?

Gene therapy could provide long-term relief from elevated nocturnal IOP

Current diagnostic methods for visual tests and imaging work are great, but can you obtain improved diagnoses with the addition of electrophysiological tests? For me, the answer is clear – after all, electrophysiology is no longer simply the domain of research institutes.

Abbott and Zeiss join forces, Valeant and Allergan continue to battle

Fusing the embryos of mice, where one contains a marker of its lineage, is a well-established technique in developmental biology research. The stripy corneas were still a surprise, though…

Transgenic mouse studies have revealed a signaling pathway that’s central to Schlemm’s canal formation

Limbal relaxing incisions were a large part of my approach to treating astigmatism in patients undergoing cataract surgery. No longer…

We look to the oldest in society to understand the contribution of poor nutrition to ophthalmic disease

Identifying corneal limbal stem cells for transplantation has been a major challenge. But now a highly specific marker of these cells has been found: ABCB5

SIRT1 appears to be an anti-aging protein that protects against weight gain, diabetes, inflammation, and even optic neuritis… in mouse models. Is SIRT1 the key to eternal youth, or simply snake oil?